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Therefore, the decreased NAD + and Acetyl-CoA synthesis in cKOt mice may both contribute to the perturbation of the TCA cycle

10.1212/NXI.0000000000000565 Neurol Neuroimmunol Neuroinflamm

The authors stress the goal is not to replace all grey infrastructure, because there are situations where there is no other choice, for example in building reservoirs to supply cities with water